In a general sense, to pursue in a manner to injure, vex or afflict; to harass with unjust punishment or penalties for supposed offenses; to inflict pain from hatred or malignity.

Appropriately, to afflict, harass, or destroy for adherence to a particular creed or system of religious principles, or to a mode of worship. Thus Nero persecuted the Christians by crucifying some, burning others, and condemning others to be worried by dogs. See Acts 22:4.

To harass with solicitations or importunity.