To separate, as from company or society, and usually to keep apart for some length of tome, or to confine in a separate state; as persons in low spirits seclude themselves from society. Let eastern tyrants from the light of heav’n Seclude their bosom slaves. Thomson.

To shut out; to prevent from entering; to preclude. Inclose your tender plants in your conservatory, secluding all entrance of cold. Evelyn.