Mischievously; destructively. This practice hath most shrewdly passed upon thee. Obs.

Vexatiously; used of slight mischief. The obstinate and schismatical are like to think themselves shrewdly hurt by being cut from that body they chos not to be of. Obs. South. Yet seem’d she not to winch, though shrewdly pained. Obs.

Archly; sagaciously; with good guess; as, I shrewdly suspect; he shrewdly observed.